Formulation and Evaluation of Orodispersible Tablet of Sulindac

Oral administration of dosage form is the most recommended mode administration, because its self-medication, accurate dose drug, and ease administration. However, trouble swallowing in geriatric patients one major negative this route, which can mentally disrupt patients. The goal study was to use direct compression method make orodispersible tablets sulindac utilizing various doses super disintegrant agents such as Sodium starch glycolate Crospovidone Croscarmellose sodium. Three distinct disintegrants were used create nine formulations with varying concentration levels. preformulation, precompression, post-compression properties powder combinations assessed. In comparison other formulations, from batch F3 containing crospovidone had superior organoleptic qualities, well outstanding drug release in-vitro disintegration time. disntegrants addition technique shown be a viable for manufacturing using method.